OSU Chemistry Physical Chemistry Laboratory



Laboratory experience in physical chemistry may accompany each semester of the lectures. The laboratory program may be separate and given as an intensive course in a single semester. Also, many programs combine physical chemistry laboratory experience with instrumental analysis and possibly with inorganic chemistry in an integated laboratory program.

What follows is a list from which a typical set of experiments in physical chemistry might be selected. Within the physical chemistry area itself, as well as in an integrated laboratory, it is common for individual experiments to combine several aspects. These aspects consist of various experimental methods and various theoretical concepts. For example, a Knudsen effusion study gives a student experience with vacuum system techniques and uses kinetic theory ideas to yield the vapor pressure of a substance such as naphthalene as a function of temperature. From this temperature dependence, Go298, Ho, and So can be determined.

In today's physical chemistry laboratory microcomputer methods should be readily available. Computers should assist in the collection of data as well as in the workup of data, in graphing data and in writing reports. Students should also have experience with spreadsheet programs. Students might also do some computer simulated experiments in which the opportunity to design much of the experiment would be emphasized. Experiments using modern computational techniques (quantum calculations, molecular modeling) are encouraged.

Report writing and error analysis are two other standard features of the physical chemistry laboratory. Students should also routinely make reasonable estimates of errors in primary experimental variables. Some experimental reports should include a substantial error analysis.

Thermodynamics

Heat of combustion; enthalpy of reaction in solution. Thermodynamic functions from the temperature dependence of an equilibrium constant or the emf, Study of a system in which activity coefficients play a prominent role.

Phase Equilibria

Solid-liquid phase diagram. Liquid-vapor phase diagram.

Kinetic Theory

Thermal conductivity of gases. Diffusion in solution. Knudsen effusion.

Kinetics

Relaxation study (first-order kinetics), possibly using laser technology. Kinetic analysis of a complex reaction. Enzyme study.

Spectroscopy

Analysis of a vibration-rotation spectrum; isotope, effects, e.g., HCl/DCl. Analysis of an electronic-vibration spectrum, e.g., I2. Atomic spectroscopy, e.g., H/D. Raman spectroscopy. NMR analysis of spin-spin coupling in a non-first-order case. Laser applications.

Macromolecules Molar weights from osmotic pressure. Light scattering. Hydrodynamics of macromolecules.

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